I saw a 60's Mustang with a Supra engine in it on streetfire.net... That was pretty bad-ass... I've also seen RX7's with LS's packed in them... So do whatever you want.
I don't know too much about Nissan's 3.5L V6, but all the really crazy 350Z's that I've seen that have had 400-600hp have all been twin turbo'd... And since you don't like boost, i'm not sure how much HP you are looking to get out of the VQ35VHR. I guess that you will know.
In order to get the stock 2.4L with that HP you'll have to throw a turbo kit on. Which would probably be on of the lighter engines but will require boost.
The LNF will get you that HP but that's another engine using boost... which you don't want...
IDK, looking at it from getting the most HP, with the easiest route of doing it would be a LS V8 swap. I know they are heavier but stock they will put out way more HP than the VQ35VHR, and have more potential still N/A'd...
But I imagine it would be do-able... You'll be the first...

but that's just my two cents...